Very typical of posted eggs. The damaged air cells will get quite big as the eggs incubate, developing a 'saddle' shape over the top of the egg (top being the rounded bottom that's facing up in the incubator, lol). Too large of an air cell however can impede the chicks growth and cause them to fail as they get bigger.
Some suggest to let the eggs rest for 24 hours before incubating, which I've read two differing reasons for - to let the air cell settle and to re-balance the CO2 levels. But others don't think it makes a whole lot of difference in the long run.
While purely anecdotal and hardly provable, here is what I have found with posted eggs and damaged air cells. Upright (rounded, 'bottom' up) is best, typical of any incubation. Tilting exacerbates the air cells damage. Twisting the egg around from the top (keeping it in it's upright position), seems to help preserve the air cell and minimise 'saddling'. The air cell doesn't move yet the embryo inside does.
What I haven't done is do a side-by-side test of tilting vs twisting from the same parcel of posted eggs, that would be the best way to tell if it makes an actual difference given all eggs will have experienced the same post handling. My experience and 'experimentation' was from two separate lots of posted eggs. Although with both I did a hatchalong with my own chickens eggs to ensure conditions in the incubator were correct and that could be eliminated as a cause should hatch rates be low.
Anyway, rambling! Yes, it's possible you can still have chicks hatch despite a wibbly-wobbly air cell. Don't expect any to hatch, that way if you get some hatch it'll be a bonus.